Design Simulation equips you with the tools to do initial basic linear analyses of a design, without the means to have expert skillset in the CAE universe. Basically, the application is a stripped down variant of Advanced Simulation, with less options and more intuitive GUI.
I've recently worked with a customer on Design Simulation, where I did a demo they wanted to use for their workgroup in order to get started with the application. I decided to make a video on it as can be seen below.
Hope you find it useful.