Yes, the MindConnect Nano (and IoT2040) can connect to third-party devices using OPC UA. If the 3rd party device does not support OPC UA, protocol converters can be used to convert to OPC UA (e.g. Matrikon converter for Mitsubishi PLC, Fanuc PLC). The connection can be done by Siemens or the customer. It is no different than connecting to Siemens devices. No development kit is required.