is the error mesage comming up by just accesing the Online-help or if you press F1 on a specific dialog or application?
Production: NX10.0.3 MP16, NX11.0.1 MP4
Development: Batch and VB Testing: NX12
I can access the NX 10.0.1 online help without problems.
Production: NX10.0.3, VERICUT 8.2, FBM, MRL 3.1.7 | TcUA 10.1 MP7 Patch 0 (10.1.7.0) | TcVis 11.4
Development: C (ITK), .NET, Tcl/Tk Testing: NX12.0 | AWC 3.4 Preparing: NX12.0
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It is still working for me but..since you and Daniele both are getting the same issue so i guess there can be something wrong also.