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Higher degree splines are inherently "stiffer"; i.e. the poles need to be moved farther to affect a similar change in a lower degree spline. In the splines that you picture, I'd be hard pressed to say that one pole structure was 'better' than the other.
If a bunch of poles are tightly grouped in one section of the spline or the control polygon starts crossing itself, then I would reevaluate the pole structure.
NX 18.104.22.168 MP11 Rev. A
GM TcE v22.214.171.124
GM GPDL v11-A.3.5.1