To get the opposite center you just need regular vector arithmetic.
Inside of the MKE there is a rule for machining holes from both sides, so you can use that formula.
lwf_2.X_ORIENTATION_D = -mwf.X_ORIENTATION_D lwf_2.Y_ORIENTATION_D = -mwf.Y_ORIENTATION_D lwf_2.Z_ORIENTATION_D = -mwf.Z_ORIENTATION_D lwf_2.X_ORIENTATION_L = -mwf.X_ORIENTATION_L lwf_2.Y_ORIENTATION_L = -mwf.Y_ORIENTATION_L lwf_2.Z_ORIENTATION_L = -mwf.Z_ORIENTATION_L lwf_2.X_POSITION = mwf.X_POSITION + mwf.DEPTH*mwf.X_ORIENTATION_D lwf_2.Y_POSITION = mwf.Y_POSITION + mwf.DEPTH*mwf.Y_ORIENTATION_D lwf_2.Z_POSITION = mwf.Z_POSITION + mwf.DEPTH*mwf.Z_ORIENTATION_D
I even think there is a detailed description in the MKE documentation about machining holes from both sides.
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