This setting is just affecting CHM files, nothing else.
I don't use chrome, so can't help with chrome related issues.
You could just delete the key or check its setting from a machine that hasn't the command applied.
Production: NX10.0.3, VERICUT 8.2, FBM, MRL 3.1.7 | TcUA 10.1 MP7 Patch 0 (10.1.7.0) | TcVis 11.4
Development: C (ITK), .NET, Tcl/Tk Testing: NX12.0 | AWC 3.4 Preparing: NX12.0
Employees of the customers, together we are strong
How to Get the Most from Your Signature in the Community
NX Customization - Best Practice Guide