Will Solid Edge work with a AMD RX 460 graphics card?
I can imagine it will, but if You will hear my opinion about graphic cards:
For many, many years I prefer nVidia.
Although they had problems with their driver in the last year, but for CAD usage they still are the best one.
Maybe others are faster but in fact of driver, problem etc. they made lesss troubles than the others.
If possible try to get a Quadro rather than a Gforce
I run the Firepro W7100 and am please with the performance.